化工社化工社 化学情報印刷レポート · 研究参考用
Benzaldehyde → HCID 178489586、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzaldehyde | HCID 240 | — |
| 反応物 | Water | HCID 962 | — |
| 反応物 | 2-Methoxyaniline | HCID 7000 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | HCID 178489586 | HCID 178489586 | 99.8% |
反応手順
To benzaldehyde (26.1 g, 25.0 mL, 0.246 mol, 1.21 equiv) in toluene (100 mL) was added 2-methoxyaniline (25.1 g, 23.0 mL, 0.204 mol, 1.00 equiv). The reaction mixture was heated to reflux with azeotropic removal of water with a Dean-Stark trap for 12 h. The reaction mixture was concentrated and dried under high vacuum to afford (E)-N-benzylidene-2-methoxyaniline as a yellow oil (43.0 g, >99% yield).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09290591B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-fe52b3cebe0e4e1ba2ed635f2dd3637d |
| 出典メモ | uspto-grants-2016_03 |