Phenol → HCID 59761643, compound

HRID 929086Notes

Reaction equation

[NH2:1][CH2:2][C@@H:3]([OH:16])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9](OC)=[C:8]([Cl:14])[C:7]=1[CH3:15].[C:17]1(O)C=CC=CC=1>>[NH2:1][CH2:2][C@@H:3]([OH:16])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([CH3:17])=[C:8]([Cl:14])[C:7]=1[CH3:15]

Participants

Reactant 2

HCID 996Phenol

HCID 59761826HCID 59761826, compound

Product 1

HCID 59761643HCID 59761643, compound

Procedure

(R)-1-Amino-3-(3-chloro-4-methoxy-2-methyl-phenoxy)-propan-2-ol tan solid, 0.51 g (starting from 3.0 mmol of phenol).

Sources & evidence

ORD record: ord-aae9cb92ed4245dc82baf452cf8eaf1b
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09290503B2

Reaction notes

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