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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929123Generated: October 26, 2026

2-Chloronicotinonitrile → 2-Methoxypyridine-3-carbonitrile

https://huagongshe.com/reaction/929123

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-ChloronicotinonitrileHCID 81079—
ReactantHCID 178418582HCID 178418582—
SolventMethanolHCID 887—
Product2-Methoxypyridine-3-carbonitrileHCID 252099—

Reaction Steps

2-Methoxy-nicotinonitrile was prepared according to the literature by reaction of the 2-chloro-nicotinonitrile with MeONa in MeOH according to Dunn, A. D.; Norrie, R.; Heterocycl. Chem.; EN; 24; 1987; 85-89.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290503B2
Source datasetuspto-grants-2016_03
ORD IDord-861025457cca4985ac158204ef5205a2
Source noteuspto-grants-2016_03