HCID 90042500, compound → 143396-56-9

HRID 929161Notes

Reaction equation

HRID 929161 reaction equation
[N:1]([C@@H:4]1[CH2:8][O:7][C@@H:6]2[C@@H:9]([N:12]=[N+]=[N-])[CH2:10][O:11][C@H:5]12)=[N+]=[N-]>CO.[Pd]>[O:7]1[CH2:8][C@@H:4]([NH2:1])[C@H:5]2[O:11][CH2:10][C@H:9]([NH2:12])[C@@H:6]12

Participants

4

Reactant 1

HCID 90042500HCID 90042500, compound

Product 1

HCID 55281067143396-56-9

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of (3R,3aR,6S,6aR)-3,6-diazidohexahydrofuro[3,2-b]furan (2.5 g, 12.74 mmol) and 5% palladium on active carbon (0.25 g) in methanol (300 mL) was hydrogenated under 40 psi in an autoclave overnight. The catalyst was removed by filtration and the solvent was evaporated to give the desired product, which was used in the next step without further purification.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-503827e261c94d06bc10ce1c6d339b2e
Source dataset
uspto-grants-2016_03
Patent number
US09290517B2

Reaction notes

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