HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929474Generated: October 30, 2026
Hexane → (S)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)prop-1-ene-2-sulfonyl chloride
https://huagongshe.com/reaction/929474
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Reactant | (S)-4-(2-iodoallyl)-2,2-dimethyl-1,3-dioxolane | HCID 86667891 | — |
| Reactant | HCID 178418306 | HCID 178418306 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | (S)-3-(2,2-dimethyl-1,3-dioxolan-4-yl)prop-1-ene-2-sulfonyl chloride | HCID 50914396 | — |
Reaction Steps
A solution of tert-butyl lithium in hexane (1.7M, 2 eq) is added dropwise to a solution of (S)-4-(2-iodoallyl)-2,2-dimethyl-1,3-dioxolane (1 eq) in diethyl ether at −78° C., and the reaction stirred at −78° C. for 30 min. Sulfuryl dichloride (1 eq) is added, the mixture warmed to room temperature and the solvents removed under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09296686B2 |
|---|
| Source dataset | uspto-grants-2016_03 |
|---|
| ORD ID | ord-358e47ce30bf4c949a3bc565df3fe2f9 |
|---|
| Source note | uspto-grants-2016_03 |
|---|
