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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929567Generated: November 3, 2026

4-Chloro-3-(trifluoromethyl)benzeneboronic acid → HCID 86718731, compound

https://huagongshe.com/reaction/929567

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-(trifluoromethyl)benzeneboronic acidHCID 2782671—
Reactant3-Bromo-5-tert-butyl-2-hydroxybenzaldehydeHCID 7172096—
Reactant5-(Tert-butyl)-2-hydroxy-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carbaldehydeHCID 86718719—
ProductHCID 86718731HCID 86718731—

Reaction Steps

5-(tert-Butyl)-4′-chloro-2-hydroxy-3′-(trifluoromethyl)-[1,1′-biphenyl]-3-carbaldehyde was prepared as a yellow oil using the procedure described in Intermediate 5 from 3-bromo-5-(tert-butyl)-2-hydroxybenzaldehyde (Intermediate 4) and 4-chloro-3-(trifluoromethyl)phenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296696B2
Source datasetuspto-grants-2016_03
ORD IDord-220c1e55b3124eeaa319b6a06cee2931
Source noteuspto-grants-2016_03