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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929572Generated: November 3, 2026

4-Chloro-3-fluorophenylboronic Acid → HCID 86718736, compound

https://huagongshe.com/reaction/929572

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-fluorophenylboronic AcidHCID 2778656—
Reactant3-Bromo-5-tert-butyl-2-hydroxybenzaldehydeHCID 7172096—
Reactant5-(Tert-butyl)-2-hydroxy-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carbaldehydeHCID 86718719—
ProductHCID 86718736HCID 86718736—

Reaction Steps

5-(tert-Butyl)-4′-chloro-3′-fluoro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde was prepared as a yellow oil using the procedure described in Intermediate 5 from 3-bromo-5-(tert-butyl)-2-hydroxybenzaldehyde (Intermediate 4) and 4-chloro-3-fluorophenylboronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296696B2
Source datasetuspto-grants-2016_03
ORD IDord-1207cc20a9d04355b6441f9c85774867
Source noteuspto-grants-2016_03