4-Chlorophenylboronic acid → HCID 86718767, compound

HRID 929589Notes

Reaction equation

HRID 929589 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:17]=[O:18])[C:5]([OH:16])=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]([Cl:15])[CH:9]=2)[CH:7]=1.[Cl:19][C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1.Cl.C(NCC1C(O)=C(C2C=CC(Cl)=C(Cl)C=2)C=C(C2C=CC(Cl)=CC=2)C=1)(C)(C)C>>[Cl:15][C:10]1[CH:9]=[C:8]([C:6]2[C:5]([OH:16])=[C:4]([CH:17]=[O:18])[CH:3]=[C:2]([C:23]3[CH:24]=[CH:25][C:20]([Cl:19])=[CH:21][CH:22]=3)[CH:7]=2)[CH:13]=[CH:12][C:11]=1[Cl:14]

Participants

4

Reactant 3

HCID 742994-Chlorophenylboronic acidHCID 86718765HCID 86718765, compoundHCID 86718768HCID 86718768, compound

Product 1

HCID 86718767HCID 86718767, compound

Procedure

3,4,4″-Trichloro-6′-hydroxy-[1,1′:3′,1″-terphenyl]-5′-carbaldehyde was prepared from 5-bromo-3′,4′-dichloro-2-hydroxy-[1,1′-biphenyl]-3-carbaldehyde and 4-chlorophenylboronic acid using the same procedure described in Intermediate 5.

Sources & evidence

ORD record
ord-b5c92bc0f5214ff8901cfc3155f1507d
Source dataset
uspto-grants-2016_03
Patent number
US09296696B2

Reaction notes

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