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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929736Generated: October 26, 2026

Thionyl Chloride → 2-(4-ethoxyphenyl)acetyl Chloride

https://huagongshe.com/reaction/929736

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
ReactantBenzeneacetic acid, 4-ethoxy-HCID 78631—
Product2-(4-ethoxyphenyl)acetyl ChlorideHCID 11629782—

Reaction Conditions

Temperature70 °C

Reaction Steps

4-Ethoxyphenylacetic acid (0.5 g, 2.8 mmol) was transferred to a 7 ml vial and dissolved in thionylchloride (3 ml). The reaction mixture was shaken at 70° C. for 21/2 hours. Thionylchloride was evaporated off and the resulting product was used unpurified.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296694B2
Source datasetuspto-grants-2016_03
ORD IDord-06de92c37c804f80ad9dfd09f1479dee
Source noteuspto-grants-2016_03