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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 929891Generated: November 1, 2026

4-Aminobenzoic Acid → 4-amino-N-(oxolan-3-ylmethyl)benzamide

https://huagongshe.com/reaction/929891

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminobenzoic AcidHCID 978—
Reactant(S)-2-methylbutanoic acidHCID 448893—
ReactantN-(4-(azetidin-3-yloxy)phenyl)-3-(pyridin-3-yl)azetidine-1-carboxamideHCID 90010911—
Product4-amino-N-(oxolan-3-ylmethyl)benzamideHCID 60920351—

Reaction Steps

The title compound was prepared as described in Example 1E, substituting (tetrahydrofuran-3-yl)methanamine for N-(4-(azetidin-3-yloxy)phenyl)-3-(pyridin-3-yl)azetidine-1-carboxamide and 4-aminobenzoic acid for (S)-2-methylbutanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296723B2
Source datasetuspto-grants-2016_03
ORD IDord-243adf76918d49b283996143e5090746
Source noteuspto-grants-2016_03