HCID 67125861, compound → HCID 54760233, compound

Participants

Reaction Steps

N-(4-(3-(3-tert-Butylisoxazol-5-yl)ureido)phenyl)-5-(1-isopropylpiperidin-4-yloxy)picolinamide (63 mg, 52%) was prepared using a procedure analogous to that described in Example 20, substituting N-(4-(3-(3-tert-butylisoxazol-5-yl)ureido)phenyl)-5-(piperidin-4-yloxy)picolinamide hydrochloride from Step 2 of this example for N-(4-(3-(5-(1,3-difluoro-2-methylpropan-2-yl)isoxazol-3-yl)ureido)phenyl)-5-(piperidin-4-yloxy)picolinamide hydrochloride used in Example 20. LC-MS (ESI) m/z 521 (M+H)+.

Provenance & Evidence