2-Chloro-6-hydrazinopyridine → HCID 89609962, compound

HRID 930000Notes

Reaction equation

HRID 930000 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[N:12]=[C:11]([C:20]([OH:22])=[O:21])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1.[Cl:23]C1N=C(NN)C=CC=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[N:13]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([Cl:23])[N:15]=3)[N:12]=[C:11]([C:20]([OH:22])=[O:21])[CH:10]=2)[CH:5]=[C:6]([F:8])[CH:7]=1

Participants

3

Reactant 2

HCID 3200042-Chloro-6-hydrazinopyridineHCID 89602575HCID 89602575, compound

Product 1

HCID 89609962HCID 89609962, compound

Procedure

1.30 g (3.97 mmol) of the compound of Example 1A is reacted analogously to the synthesis of the compound of Example 20A with 854 mg (5.95 mmol) of 6-chloropyridin-2-yl-hydrazine. After hydrolysis, 815 mg (58% of theory) of the title compound is obtained.

Sources & evidence

ORD record
ord-81e64ce18fea4baeb21124c6e74710bd
Source dataset
uspto-grants-2016_03
Patent number
US09296720B2

Reaction notes

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