HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66687731, compound → 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-chloro-2-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66687731 | HCID 66687731 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Bromo-5-trifluoromethoxyphenyl)-1-(6-chloropyridin-2-yl)-1H-pyrazole-3-carboxylic acid | HCID 89609956 | — |
| Product | 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-chloro-2-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one | HCID 86574458 | — |
Reaction Steps
75 mg (0.16 mmol) of the compound of Example 38A is reacted analogously to the synthesis of the compound of Example 1 with 22 mg (0.18 mmol) of 4-imidazolinone-hydrochloride. 65 mg (75% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c9730ce70b6b4d63bf0077079e78f613 |
| Source note | uspto-grants-2016_03 |