HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiazolidine → [5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazol-3-yl]-thiazolidin-3-yl-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiazolidine | HCID 10444 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | HCID 89602527 | HCID 89602527 | — |
| Product | [5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(3-pyridyl)pyrazol-3-yl]-thiazolidin-3-yl-methanone | HCID 86574477 | — |
Reaction Steps
130 mg (0.30 mmol) of the compound of Example 39A is reacted analogously to the synthesis of the compound of Example 1 with 0.03 ml (0.33 mmol) of thiazolidine. 116 mg (77% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-2d47d9f3014b43a6bbc098c1705e0116 |
| Source note | uspto-grants-2016_03 |