HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66687731, compound → 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-fluoro-3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66687731 | HCID 66687731 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | HCID 89609969 | HCID 89609969 | — |
| Product | 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(6-fluoro-3-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one | HCID 86574255 | — |
Reaction Steps
75 mg (0.17 mmol) of the compound of Example 42A is reacted analogously to the synthesis of the compound of Example 1 with 23 mg (0.19 mmol) of 4-imidazolinone-hydrochloride. 64 mg (74% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-fc9d5c69a68d403bb6888731de6e16fe |
| Source note | uspto-grants-2016_03 |