HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66687731, compound → 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(4-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66687731 | HCID 66687731 | — |
| Reactant | HCID 71576484 | HCID 71576484 | — |
| Reactant | 5-(3-Bromo-5-trifluoromethoxyphenyl)-1-(pyridin-4-yl)-1H-pyrazole-3-carboxylic acid | HCID 89602599 | — |
| Product | 1-[5-[3-Bromo-5-(trifluoromethoxy)phenyl]-1-(4-pyridyl)pyrazole-3-carbonyl]imidazolidin-4-one | HCID 86574625 | — |
Reaction Steps
22 mg (0.05 mmol) of the compound of Example 45A is reacted analogously to the synthesis of the compound of Example 1 with 7 mg (0.06 mmol) of 4-imidazolinone-hydrochloride. 24 mg (94% of theory) of the title compound is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296720B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-6c5bf239cca144e8bf9d2ea4e121a2c1 |
| Source note | uspto-grants-2016_03 |