HCID 86615901, compound → HCID 86615900, compound

HRID 930173Notes

Reaction equation

HRID 930173 reaction equation
[C:1]1([C:7]([CH2:13][S:14]([OH:17])(=[O:16])=[O:15])=[CH:8][S:9]([OH:12])(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C1COCC1.O.[Pd]>[C:1]1([CH:7]([CH2:13][S:14]([OH:17])(=[O:16])=[O:15])[CH2:8][S:9]([OH:12])(=[O:11])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 1

HCID 86615901HCID 86615901, compound

Product 1

HCID 86615900HCID 86615900, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 21881883Oxolane--water (1/1)Solvent

Procedure

To 2-phenyl-propene-1,3-disulfonic acid (J. Amer. Chem. Soc., 66, 1105-9 (1944)) in THF-water (1:1) is added 10 wt % of 5% palladium on carbon and the mixture hydrogenated on a Parr shaker under 15 lb hydrogen pressure until the reaction is complete by thin layer chromatography (TLC). The mixture is filtered (Celite) and concentrated in vacuo to afford the title compound.

Workup

  1. filtrationThe mixture is filtered (Celite)
  2. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-3bcf2b7123394a57987732476e8b6717
Source dataset
uspto-grants-2016_03
Patent number
US09296726B2

Reaction notes

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