反应详情

The titled compound was synthesized by procedure and steps analogous to those described in Method B, Step 2, Example 8 above, but using (4S,6S)-4-(5-amino-2,3-difluorophenyl)-4-methyl-6-(trifluoromethyl)-5,6-dihydro-4H-1,3-oxazin-2-amine (17i, Example 163, Method Y step 9) and 8-chloro-5-fluoro-1,7-naphthyridine-3-carbonitrile (intermediate 17) in step 2. MS m/z=481.1 [M+H]+. Calculated for C21H14F6N6O: 480.4