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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 930471Generated: October 29, 2026

2,2,2-Trifluoroethanol → 3-Methyl-5-(2,2,2-trifluoroethoxy)pyrazine-2-carboxylic acid

https://huagongshe.com/reaction/930471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-TrifluoroethanolHCID 6409—
Reactant5-Methoxy-3-methylpyrazine-2-carboxylic acidHCID 66665830—
Product3-Methyl-5-(2,2,2-trifluoroethoxy)pyrazine-2-carboxylic acidHCID 86728147—

Reaction Steps

The title compound was synthesized according to Intermediate 13, using 2,2,2,-trifluoroethanol (Aldrich) in Step 4. MS m/z=237 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296734B2
Source datasetuspto-grants-2016_03
ORD IDord-97f6f9a3146040c3bca5c8e8d6663be9
Source noteuspto-grants-2016_03