Methyl 3-chloro-5-methoxypicolinate → 3-Chloro-5-methoxypicolinic acid

HRID 930474Notes

Reaction equation

HRID 930474 reaction equation
FC(F)(F)COC1C(C(N)=O)=NC=CC=1.[Cl:16][C:17]1[C:18]([C:25]([O:27]C)=[O:26])=[N:19][CH:20]=[C:21]([O:23][CH3:24])[CH:22]=1>>[Cl:16][C:17]1[C:18]([C:25]([OH:27])=[O:26])=[N:19][CH:20]=[C:21]([O:23][CH3:24])[CH:22]=1

Participants

3

Reactant 2

HCID 21696614Methyl 3-chloro-5-methoxypicolinateHCID 66644029HCID 66644029, compound

Product 1

HCID 676098923-Chloro-5-methoxypicolinic acid

Procedure

Using an analogous reaction to that described for Intermediate 5, step 2 methyl 3-chloro-5-methoxypicolinate was converted to the title compound. MS m/z=188 (M+H).

Workup

  1. customan analogous reaction to

Sources & evidence

ORD record
ord-900e2a4f1bb1401e8b8cb2d1fc49d0f3
Source dataset
uspto-grants-2016_03
Patent number
US09296734B2

Reaction notes

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