反应详情

温度

170 °C

{4-Benzylamino-5-[(1,5-dimethyl-6-oxo-1,6-dihydro-pyridine-3-carbonyl)-amino]-pyridin-2-yl}-carbamic acid tert-butyl ester II-16″ (2.000 g; 4.315 mmol) is suspended in acetic acid (5.190 g; 86 mmol) in a microwave vial and heated in a CEM microwave at 170° C. for 5 h. The reaction mixture is then concentrated under reduced pressure. The residue is used in the next step without further purification.

1. concentrationThe reaction mixture is then concentrated under reduced pressure
2. customThe residue is used in the next step without further purification