HCID 117892035, compound → HCID 90161013, compound

Participants

Reaction Steps

5-(3,6-dihydro-2H-pyran-4-yl)-2-nitro-N-(pyridin-2-ylmethyl)aniline E-1.9′ (82 mg; 0.26 mmol) is dissolved in THF (25 ml) and filled into a Büchi autoclave. RaNi is added and the reaction is hydrogenated with 5 bar hydrogen pressure overnight. The reaction mixture is filtered on a plug of celite. The filtrate is then concentrated under reduced pressure. The product is used in the next step without further purification.

Provenance & Evidence