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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 930692Generated: October 29, 2026

4-chloropyridine N-oxide → HCID 68657451, compound

https://huagongshe.com/reaction/930692

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-chloropyridine N-oxideHCID 70724—
Reactant(4-Fluoro-2-methoxyphenyl)boronic acidHCID 2782672—
ProductHCID 68657451HCID 6865745187.4%

Reaction Steps

4-Chloropyridine-N-oxide (305 mg, 2.35 mmol), 4-fluoro-2-methoxyphenylboronic acid (1.0 g, 8.8 mmol) were reacted according to the procedure of Example 39 (step a) to provide the title compound (450 mg, 87%) as a purple solid: 1H NMR (300 MHz, CDCl3) δ 8.21 (d, J=7.2 Hz, 2H), 7.45 (d, J=7.2 Hz, 2H), 7.31 (d, J=6.5 Hz, 1H), 6.80-6.71 (m, 2H), 3.85 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296743B2
Source datasetuspto-grants-2016_03
ORD IDord-d07b150ff61b439ca997b923dbaf8ff5
Source noteuspto-grants-2016_03