Morpholine → HCID 77106850, compound

HRID 930819Notes

Reaction equation

HRID 930819 reaction equation
[O:1]=[C:2]1[N:7]2[CH2:8][CH2:9][CH2:10][N:11]([CH2:12][C:13]([OH:15])=O)[C:6]2=[CH:5][C:4]([O:16][CH2:17][C:18]2[CH:23]=[C:22]([F:24])[C:21]([F:25])=[C:20]([F:26])[CH:19]=2)=[N:3]1.[NH:27]1[CH2:32][CH2:31][O:30][CH2:29][CH2:28]1>>[O:30]1[CH2:31][CH2:32][N:27]([C:13](=[O:15])[CH2:12][N:11]2[CH2:10][CH2:9][CH2:8][N:7]3[C:2](=[O:1])[N:3]=[C:4]([O:16][CH2:17][C:18]4[CH:23]=[C:22]([F:24])[C:21]([F:25])=[C:20]([F:26])[CH:19]=4)[CH:5]=[C:6]23)[CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 8083MorpholineHCID 90304455HCID 90304455, compound

Product 1

HCID 77106850HCID 77106850, compound

Procedure

The title compound was prepared by a procedure similar to that described for E13 starting from 2-(6-oxo-8-((3,4,5-trifluorobenzyl)oxy)-2,3,4,6-tetrahydro-1H-pyrimido[1,6-a]pyrimidin-1-yl) acetic acid and morpholine.

Sources & evidence

ORD record
ord-a4a74afb4dac48728c6e5ee186622aa7
Source dataset
uspto-grants-2016_03
Patent number
US09296755B2

Reaction notes

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