HCID 71616298, compound → HCID 86721044, compound

HRID 930863Notes

Reaction equation

HRID 930863 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:26]=[CH:27][C:28]=1[F:29])[O:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][C:7]=1[C:15]1[C:16]2[CH:25]=[CH:24][NH:23][C:17]=2[C:18](=[O:22])[N:19]([CH3:21])[CH:20]=1.CN1C=C(C2C=C([N+]([O-])=O)C=CC=2OC2C=CC=CC=2)C2C=CNC=2C1=O>>[NH2:12][C:9]1[CH:10]=[CH:11][C:6]([O:5][C:4]2[CH:26]=[CH:27][C:28]([F:29])=[C:2]([F:1])[CH:3]=2)=[C:7]([C:15]2[C:16]3[CH:25]=[CH:24][NH:23][C:17]=3[C:18](=[O:22])[N:19]([CH3:21])[CH:20]=2)[CH:8]=1

Participants

3

Reactant 2

HCID 71616298HCID 71616298, compoundHCID 86721045HCID 86721045, compound

Product 1

HCID 86721044HCID 86721044, compound

Procedure

Example 48b was prepared according to the procedure used for the preparation of Example 3, substituting the product of Example 48a for the product of Example 2b, to provide the title compound.

Workup

  1. customExample 48b was prepared
  2. customused for the preparation of Example 3

Sources & evidence

ORD record
ord-6beacee930d64037a84dfcedf1dbccff
Source dataset
uspto-grants-2016_03
Patent number
US09296741B2

Reaction notes

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