Cyclohexylamine → 3-Bromo-4-(cyclopropylmethylamino)benzenesulfonamide

HRID 930896Notes

Reaction equation

HRID 930896 reaction equation
[CH:1]1([NH2:7])[CH2:6][CH2:5][CH2:4]CC1.[Br:8][C:9]1[CH:10]=[C:11]([S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][C:14]=1F>>[Br:8][C:9]1[CH:10]=[C:11]([S:16]([NH2:19])(=[O:18])=[O:17])[CH:12]=[CH:13][C:14]=1[NH:7][CH2:1][CH:6]1[CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 790405443-Bromo-4-fluorobenzenesulfonamide

Product 1

HCID 437457443-Bromo-4-(cyclopropylmethylamino)benzenesulfonamide

Procedure

Example 238a was prepared according to the procedure used for the preparation of Example 96a, substituting cyclopropylmethanamine for cyclohexanamine, and 3-bromo-4-fluorobenzenesulfonamide for Example 86a, respectively, to provide the title compound.

Workup

  1. customExample 238a was prepared
  2. customused for the preparation of Example 96a

Sources & evidence

ORD record
ord-2592102e6af74f11bfbd7a8c9b2158b2
Source dataset
uspto-grants-2016_03
Patent number
US09296741B2

Reaction notes

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