HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Pyrazole-4-carbonitrile → 1-(4-cyano-1H-pyrazol-1-yl)cyclopropane-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Pyrazole-4-carbonitrile | HCID 564449 | — |
| Reactant | 1-(4-Fluoro-1H-pyrazol-1-yl)cyclopropanecarboxylic acid | HCID 89853336 | — |
| Product | 1-(4-cyano-1H-pyrazol-1-yl)cyclopropane-1-carboxylic acid | HCID 117966299 | — |
Reaction Steps
The title compound was prepared by a method analogous to Intermediate 4 but using 1H-pyrazole-4-carbonitrile in Step 1. 1H NMR (400 MHz, CDCl3) δ 1.65 (m, 2H), 1.89 (m, 2H), 7.80 (s, 1H), 8.02 (s, 1H); MS (ES−) (M−H) 176.4, LCMS retention time: 1.04 minutes (Method M).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296745B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-0314fb7803f44ec39f60298230dbc7cf |
| Source note | uspto-grants-2016_03 |