Acetyl chloride → HCID 117966584, compound

Participants

Reaction Steps

Into a 4 mL vial was added 1-(4-(trifluoromethyl)phenyl)cyclopropanecarbonitrile (21 mg, 0.1 mmol), ethanol (70 μL) and acetyl chloride (56 μL, 0.792 mmol). The reaction mixture was stirred at room temperature for 18 h. The solvent was removed under reduced pressure to afford the title compound as a white solid (30 mg). The material was used without further purification. 1H NMR (500 MHz, CD3OD) δ 1.45 (t, 3H), 1.61-1.66 (m, 2H), 1.95-2.00 (m, 2H), 4.44 (d, 2H), 7.70 (d, 2H), 7.75 (d, 2H).

Provenance & Evidence