1-(2-Methoxyphenyl)cyclopropane-1-carbonitrile → Ethyl 1-(2-methoxyphenyl)cyclopropanecarbimidate hydrochloride

HRID 931136Notes

Reaction equation

HRID 931136 reaction equation
[ClH:1].CO[C:4]1[CH:9]=[CH:8][C:7]([C:10]2([C:13](=[NH:17])[O:14][CH2:15][CH3:16])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1.[CH3:18][O:19]C1C=CC=CC=1C1(C#N)CC1>>[ClH:1].[CH3:18][O:19][C:6]1[CH:5]=[CH:4][CH:9]=[CH:8][C:7]=1[C:10]1([C:13](=[NH:17])[O:14][CH2:15][CH3:16])[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 102196291-(2-Methoxyphenyl)cyclopropane-1-carbonitrileHCID 89854594Ethyl 1-(4-methoxyphenyl)cyclopropanecarbimidate hydrochloride

Product 1

HCID 89854623Ethyl 1-(2-methoxyphenyl)cyclopropanecarbimidate hydrochloride

Procedure

The title compound (50 mg, oil) was prepared by a method analogous to the one used for Intermediate 48 but using 1-(2-methoxyphenyl)cyclopropanecarbonitrile.

Sources & evidence

ORD record
ord-02d4f5cdb95746b6ba611cd7f8094d35
Source dataset
uspto-grants-2016_03
Patent number
US09296745B2

Reaction notes

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