反应详情

A solution of (R)-ethyl 1-(6-amino-5-nitropyridin-2-yl)piperidine-3-carboxylate (1.0 g, 6.60 mmol) in ethanol (30 mL) was added to a suspension of 10% palladium-on-carbon (500 mg) in ethanol at room temperature. The reaction mixture was hydrogenated for 4 h using a balloon filled with hydrogen gas. The mixture was filtered through a pad of Celite and the filtrate was used without further purification.

1. filtrationThe mixture was filtered through a pad of Celite
2. customthe filtrate was used without further purification