Dimethylamine → HCID 68436320, compound

HRID 931359Notes

Reaction equation

HRID 931359 reaction equation
C([N:8]1[CH2:17][CH2:16][C:15]2[N:14]=[C:13](Cl)[CH:12]=[CH:11][C:10]=2[CH2:9]1)C1C=CC=CC=1.[CH3:19][NH:20][CH3:21]>>[CH3:19][N:20]([CH3:21])[C:13]1[CH:12]=[CH:11][C:10]2[CH2:9][NH:8][CH2:17][CH2:16][C:15]=2[N:14]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 162287476-Benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine

Product 1

HCID 68436320HCID 68436320, compound

Procedure

N,N-Dimethyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-amine was prepared via reaction of 6-benzyl-2-chloro-5,6,7,8-tetrahydro-1,6-naphthyridine with dimethylamine, followed by hydrogenation to remove the protecting group.

Workup

  1. customto remove the protecting group

Sources & evidence

ORD record
ord-20e4e93185884700b4b3bdf5e95529b5
Source dataset
uspto-grants-2016_03
Patent number
US09296761B2

Reaction notes

Loading…