HCID 68278445, compound → HCID 53213360, compound

Participants

Reaction Steps

Reaction of benzoate 31 (217 mg, 0.56 mmol) and 6 M HCl (10 mL) gave acid 32 (173 mg, 83%) as a white solid: mp (H2O) 287-290° C.; 1H NMR δ 13.16 (br s, 1H, CO2H), 8.05 (br d, J=8.5 Hz, 2H, H-2, H-6), 7.92 (br d, J=8.5 Hz, 2H, H-3, H-5), 7.63 (br s, 1H, H-2′), 7.54-7.59 (m, 2H, H-4′, H-6′), 7.50 (t, J=7.6 Hz, 1H, H-5′), 4.65 (s, 2H, CH2SO2), 2.37 (s, 3H, CH3), 2.16 (s, 3H, CH3); MS m/z 372.6 (MH+, 100%). Anal. calcd for C19H17NO5S: C, 61.74; H, 4.61; N, 3.77. Found: C, 61.51; H, 4.56; N, 3.80%.

Provenance & Evidence