Hydrochloric Acid → HCID 68278000, compound

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Reaction Steps

A solution of methyl 4-(4-((4-((dimethylamino)methyl)phenylsulfonyl)methyl)-5-methyloxazol-2-yl)benzoate (900 mg, 1.56 mmol, 1.00 equiv, 74%) in 6N hydrochloric acid (25 mL) was refluxed overnight. The resulting solution cooled to room temperature and then diluted with 30 mL of water/ice. The solid was removed by filtration out and washed with 3×20 mL of water. The filtrate and washings were combined and concentrated in vacuum to give 0.6 g (84%) of 4-(4-((4-((dimethylamino)methyl)phenylsulfonyl)methyl)-5-methyloxazol-2-yl)benzoic acid hydrochloride as a yellow solid. LC-MS: (ES, m/z): 415 [M+H]+, 395, 120.

Provenance & Evidence