HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Benzeneacetyl chloride, 4-bromo-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Benzeneacetic acid, 4-bromo- | HCID 74654 | — |
| Product | Benzeneacetyl chloride, 4-bromo- | HCID 181552 | 92% |
Reaction Steps
A solution of 2-(4-bromophenyl)acetic acid (20.0 g, 93.46 mmol, 1.00 equiv) in thionyl chloride (40 mL) was refluxed for 2 h. The resulting mixture was concentrated under vacuum to give 20 g (92%) of 2-(4-bromophenyl)acetyl chloride as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296732B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-a337be744cdd40b696d3325b9d5eb624 |
| Source note | uspto-grants-2016_03 |