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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 931720Generated: November 2, 2026

5-(4-Chlorophenyl)-7-methyl-6-vinylquinoline → (S)-1-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)ethane-1,2-diol

https://huagongshe.com/reaction/931720

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Chlorophenyl)-7-methyl-6-vinylquinolineHCID 66631046—
Reactant(S)-1-(7-chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl)ethane-1,2-diolHCID 66633446—
Product(S)-1-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)ethane-1,2-diolHCID 66633556—

Reaction Steps

Compound 3H was prepared following the procedure used to prepare compound 1H of Example 1, except that 5-(4-chlorophenyl)-7-methyl-6-vinyl-quinoline (3G) was used instead of compound 1G. LCMS-ESI+ (m/z): 314.2, 316.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296758B2
Source datasetuspto-grants-2016_03
ORD IDord-2e2bbf1b7adf4cee89f8247db757cf15
Source noteuspto-grants-2016_03