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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 931721Generated: October 30, 2026

(S)-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)-2-hydroxyethyl pivalate → (S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)ethyl pivalate

https://huagongshe.com/reaction/931721

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)-2-hydroxyethyl pivalateHCID 66631261—
Reactant(S)-2-tert-butoxy-2-(7-chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl)ethyl pivalateHCID 66631574—
Product(S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)ethyl pivalateHCID 66631713—

Reaction Steps

Compound 3J was prepared following the procedure used to prepare compound 1J of Example 1, except that (S)-2-(5-(4-chlorophenyl)-7-methylquinolin-6-yl)-2-hydroxyethyl pivalate (3I) was used instead of compound 1I. LCMS-ESI+ (m/z): 454.3, 456.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296758B2
Source datasetuspto-grants-2016_03
ORD IDord-cb4320f3a86045e8ba71d0f15a3e8261
Source noteuspto-grants-2016_03