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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 931726Generated: November 1, 2026

7-Chloro-5-(4-chlorophenyl)-2-methyl-6-vinylquinoline → 8-(4-Chlorophenyl)-6-methyl-7-vinylquinoline

https://huagongshe.com/reaction/931726

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-5-(4-chlorophenyl)-2-methyl-6-vinylquinolineHCID 66630622—
Reactant8-(4-Chlorophenyl)-6-methylquinolin-7-yl trifluoromethanesulfonateHCID 86691976—
Product8-(4-Chlorophenyl)-6-methyl-7-vinylquinolineHCID 66630487—

Reaction Steps

Compound 4E was prepared following the procedure used to prepare compound 1G of Example 1, except that 8-(4-chlorophenyl)-6-methylquinolin-7-yl trifluoromethanesulfonate (4D) was used instead of compound 1F. LCMS-ESI+ (m/z): 280.2, 282.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09296758B2
Source datasetuspto-grants-2016_03
ORD IDord-fbbdb54f96614cfd828ceeecb7d475e3
Source noteuspto-grants-2016_03