HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-tert-butoxy-2-(7-chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl)ethanol → (2S)-2-tert-butoxy-2-(5-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2,7-dimethylquinolin-6-yl)ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-tert-butoxy-2-(7-chloro-5-(4-chlorophenyl)-2-methylquinolin-6-yl)ethanol | HCID 66631657 | — |
| Reactant | (2S)-2-tert-butoxy-2-(5-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2,7-dimethylquinolin-6-yl)ethyl pivalate | HCID 66631664 | — |
| Product | (2S)-2-tert-butoxy-2-(5-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2,7-dimethylquinolin-6-yl)ethanol | HCID 66632100 | — |
Reaction Steps
Compound 6C was prepared following the procedure used to prepare compound 1K of Example 1 except that (2S)-2-tert-butoxy-2-(5-(2,3-dihydropyrano[4,3,2-de]quinolin-7-yl)-2,7-dimethylquinolin-6-yl)ethyl pivalate (6B) was used instead of compound 1J. LCMS-ESI+ (m/z): 433.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09296758B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-cd67968ddc6442cab657f59094dad9bd |
| Source note | uspto-grants-2016_03 |