HRID931779

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2c(ccc(C)[n+]2[O-])c1C1=CCCCC1

HCID66631690

未命名化合物

结构：CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(COC(C)=O)ccc2c1-c1ccc(Cl)cc1

HCID86691980

未命名化合物

结构：Cc1cc(-c2ccc(Cl)cc2)c2ccc(C)[n+]([O-])c2c1

HCID86691981

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)[C@@H](OC(C)(C)C)c1c(C)cc2nc(COC(C)=O)ccc2c1C1=CCCCC1

HCID68594582

未命名化合物

PROCEDURE

实验过程

(S)-Ethyl 2-(2-(acetoxymethyl)-5-cyclohexenyl-7-methylquinolin-6-yl)-2-tert-butoxyacetate was prepared following the procedure used to prepare compound (S)-ethyl 2-(2-(acetoxymethyl)-5-(4-chlorophenyl)-7-methylquinolin-6-yl)-2-tert-butoxyacetate of Example 16, except that (S)-6-(1-tert-butoxy-2-ethoxy-2-oxoethyl)-5-cyclohexenyl-2,7-dimethylquinoline 1-oxide was used instead of 2-ethoxy-2-oxoethyl)-5-(4-chlorophenyl)-2,7-dimethylquinoline 1-oxide. LCMS-ESI+ (m/z): 454.3 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-03ebc554f083472894c03113d43fd37b
来源数据集: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09296758B2
来源说明: uspto-grants-2016_03

反应 SMILES

[C:1]([O:4][CH2:5][C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][C:10]([CH3:34])=[C:11]([C@H:23]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])[C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:12]=2[C:16]2[CH:21]=[CH:20][C:19](Cl)=[CH:18][CH:17]=2)[N:7]=1)(=[O:3])[CH3:2].C(O[C@@H](C1C(C2CCCCC=2)=C2C(=CC=1C)[N+]([O-])=C(C)C=C2)C(OCC)=O)(C)(C)C.ClC1C=CC(C2C=C(C)C=C3C=2C=CC(C)=[N+]3[O-])=CC=1>>[C:1]([O:4][CH2:5][C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][C:10]([CH3:34])=[C:11]([C@H:23]([O:29][C:30]([CH3:33])([CH3:32])[CH3:31])[C:24]([O:26][CH2:27][CH3:28])=[O:25])[C:12]=2[C:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH:17]=2)[N:7]=1)(=[O:3])[CH3:2]