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HRID931805

反应详情

EQUATION

反应方程式

HRID 931805 的结构方程式

REACTANTS

反应物

3
结构：Cc1cc2nc(N3CCOCC3)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C
HCID66630867

未命名化合物

结构：Cc1cc2nc(N3CCOCC3)ccc2c(-c2ccc(Cl)cc2)c1[C@@H](COC(=O)C(C)(C)C)OC(C)(C)C
HCID66631939

未命名化合物

结构：Cc1cc2c(ccc3nncn32)c(-c2ccc(Cl)cc2)c1[C@@H](CO)OC(C)(C)C
HCID66633417

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc2c(ccc3nncn32)c(-c2ccc(Cl)cc2)c1[C@H](OC(C)(C)C)C(=O)O
HCID66634082

未命名化合物

PROCEDURE

实验过程

(S)-2-tert-butoxy-2-(6-(4-chlorophenyl)-8-methyl-[1,2,4]triazolo[4,3-a]quinolin-7-yl)acetic acid was prepared in a similar manner as compound ((S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-morpholinoquinolin-6-yl)acetic acid of Example 29 except using (S)-2-tert-butoxy-2-(6-(4-chlorophenyl)-8-methyl-[1,2,4]triazolo[4,3-a]quinolin-7-yl)ethanol instead of ((S)-2-tert-butoxy-2-(5-(4-chlorophenyl)-7-methyl-2-morpholinoquinolin-6-yl)ethanol. 1H-NMR 400 MHz (CD3OD) δ 9.95 (s, 1 H), 8.34 (s, 1 H), 7.6 (m, 3 H), 7.54 (m, 1 H), 7.35 (m, 2 H), 5.17 (s, 1 H), 2.75 (s, 3 H), 0.99 (s, 9 H); LCMS-ESI+ (m/z): [M+H]+ calcd for C23H23ClN3O3: 424.1. Found: 424.2; LCMS-EST (m/z): [M−H]− calcd for C23H21ClN3O3: 422.1Found: 421.9.