4-Isopropyl-5,5-dimethyl-oxazolidin-2-one → 3-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-methylsulfonylphenyl]-5,5-dimethyl-4-propan-2-yl-1,3-oxazolidin-2-one

HRID 93206Notes

Reaction equation

HRID 93206 reaction equation
[Br:1][c:2]1[cH:3][c:4]([S:24](=[O:25])(=[O:26])[CH3:27])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1.[CH:28]([CH3:29])([CH3:30])[CH:31]1[NH:32][C:33](=[O:38])[O:34][C:35]1([CH3:36])[CH3:37]>>[c:2]1([N:32]2[CH:31]([CH:28]([CH3:29])[CH3:30])[C:35]([CH3:36])([CH3:37])[O:34][C:33]2=[O:38])[cH:3][c:4]([S:24](=[O:25])(=[O:26])[CH3:27])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][N:13]([c:16]3[n:17][cH:18][c:19]([CH3:23])[cH:20][c:21]3[CH3:22])[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 36126874-Isopropyl-5,5-dimethyl-oxazolidin-2-oneHCID 58484505(4-Bromo-2-methanesulfonylphenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone

Product 1

HCID 772759553-[4-[4-(3,5-Dimethyl-2-pyridinyl)piperazine-1-carbonyl]-3-methylsulfonylphenyl]-5,5-dimethyl-4-propan-2-yl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-e4962b5fa58147d9978a5714300a7b6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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