1-Propanone, 1-(4-pyridyl)- → 1-(Pyridin-4-yl)propan-1-ol

HRID 932181Notes

Reaction equation

HRID 932181 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7](=[O:10])[CH2:8][CH3:9])=[CH:3][CH:2]=1.N1C=CC=C(C(O)CC)C=1>>[N:1]1[CH:6]=[CH:5][C:4]([CH:7]([OH:10])[CH2:8][CH3:9])=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 743431-Propanone, 1-(4-pyridyl)-HCID 110839421-(Pyridin-3-yl)propan-1-ol

Product 1

HCID 146845361-(Pyridin-4-yl)propan-1-ol

Procedure

The title compound was prepared from 1-(pyridin-4-yl) propan-1-one (purchased from Waterstone Technology) following a procedure similar to the one described for the synthesis of 1-(pyridin-3-yl) propan-1-ol (Example 233, Step A). Mass Spectrum (ESI) m/z=138.0 (M+1).

Sources & evidence

ORD record
ord-de5566e2e3214a308b35cd17471f6e61
Source dataset
uspto-grants-2016_03
Patent number
US09296736B2

Reaction notes

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