HCID 18769618, compound → HCID 67998794, compound

HRID 932183Notes

Reaction equation

HRID 932183 reaction equation
[F:1][C:2]([F:14])([F:13])[C:3]1[N:8]=[C:7]([CH:9](O)[CH2:10][CH3:11])[CH:6]=[CH:5][CH:4]=1.[Br:15]C(C1C=CC=CN=1)CCC>>[Br:15][CH:9]([C:7]1[CH:6]=[CH:5][CH:4]=[C:3]([C:2]([F:14])([F:13])[F:1])[N:8]=1)[CH2:10][CH3:11]

Participants

3

Reactant 2

HCID 18769618HCID 18769618, compoundHCID 67999216HCID 67999216, compound

Product 1

HCID 67998794HCID 67998794, compound

Procedure

The title compound was prepared from 1-(6-(trifluoromethyl)pyridin-2-yl)propan-1-ol (Example 238, Step A) following a procedure similar to the one described for the synthesis of 2-(1-bromobutyl)pyridine (Example 231, Step B). Mass Spectrum (ESI) m/z=268.0 (M+1) and 269.9 (M+1).

Sources & evidence

ORD record
ord-0036c66d2db94ee5a4e5fb7e09b85727
Source dataset
uspto-grants-2016_03
Patent number
US09296736B2

Reaction notes

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