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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 932308Generated: October 25, 2026

Chloride → Tert-butyl 4-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)-3-oxobutanoate

https://huagongshe.com/reaction/932308

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantMagnesium CationHCID 888—
ReactantDimethylformamideHCID 6228—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactant1,1'-CarbonyldiimidazoleHCID 68263—
Reactant2-(2,2-Dimethyl-5-oxo-1,3-dioxolan-4-yl)acetic acidHCID 357864—
ReactantTert-butyl malonateHCID 21883978—
ProductTert-butyl 4-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)-3-oxobutanoateHCID 19073721—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-454db0d9197d480b9d33ae4ef49735f3
Source noteValidation data from https://doi.org/10.1039/C8SC04228D