HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 932359Generated: November 1, 2026
Hydrochloric Acid → 4-(1-(5-(Difluoromethoxy)pyrimidin-2-yl)piperidin-4-yloxy)-1-(4-(methylsulfonyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile
https://huagongshe.com/reaction/932359
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-(Difluoromethoxy)-2-(methylsulfonyl)pyrimidine | HCID 67072624 | — |
| Reactant | 1-(4-Methylsulfonylphenyl)-6-oxo-4-piperidin-4-yloxypyridazine-3-carbonitrile | HCID 67444877 | — |
| Product | 4-(1-(5-(Difluoromethoxy)pyrimidin-2-yl)piperidin-4-yloxy)-1-(4-(methylsulfonyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile | HCID 44621226 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-78f67e2e1e544b1181690a2bd8a7e1f5 |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
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