4-Fluorobenzyl bromide → 4-[(4-Fluorobenzyl)oxy]-6-phenyl-2-pyridin-4-ylpyrimidine
Reaction equation
[F:20][c:21]1[cH:22][cH:23][c:24]([CH2:25][Br:26])[cH:27][cH:28]1.[c:1]1(-[c:7]2[cH:8][c:9]([OH:19])[n:10][c:11](-[c:13]3[cH:14][cH:15][n:16][cH:17][cH:18]3)[n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][c:9]([O:19][CH2:25][c:24]3[cH:23][cH:22][c:21]([F:20])[cH:28][cH:27]3)[n:10][c:11](-[c:13]3[cH:14][cH:15][n:16][cH:17][cH:18]3)[n:12]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-eaebfccb74bc47b19febf42d26367025
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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