1-(2-Methoxyphenyl)piperazine → [1-[(3-Chlorophenyl)methyl]-4-[(2,4-difluorophenyl)methyl-methylamino]pyrrolidin-2-yl]-[4-(2-methoxyphenyl)piperazin-1-yl]methanone
Reaction equation
[CH3:28][O:29][c:30]1[c:31]([N:36]2[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]2)[cH:32][cH:33][cH:34][cH:35]1.[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH:7]([C:22](=[O:23])[OH:24])[CH2:8][CH:9]([N:11]([CH3:12])[CH2:13][c:14]3[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]3)[CH2:10]2)[cH:25][cH:26][cH:27]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[CH:7]([C:22](=[O:24])[N:39]3[CH2:38][CH2:37][N:36]([c:31]4[c:30]([O:29][CH3:28])[cH:35][cH:34][cH:33][cH:32]4)[CH2:41][CH2:40]3)[CH2:8][CH:9]([N:11]([CH3:12])[CH2:13][c:14]3[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]3)[CH2:10]2)[cH:25][cH:26][cH:27]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-66e91418dbed4a9e80da91d72585a1e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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