Dichloromethane → N-(3,4-Difluorobenzyl)-6-hydroxy-2-isopropyl-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamide
Reaction equation
[B:34]([Br:35])([Br:36])[Br:37].[Cl:38][CH2:39][Cl:40].[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([CH:27]([CH3:28])[CH3:29])[n:11]([CH2:20][c:21]3[n:22][cH:23][cH:24][cH:25][cH:26]3)[c:12]3[cH:13][c:14]([O:18][CH3:19])[cH:15][cH:16][c:17]23)[cH:30][cH:31][c:32]1[F:33]>>[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([CH:27]([CH3:28])[CH3:29])[n:11]([CH2:20][c:21]3[n:22][cH:23][cH:24][cH:25][cH:26]3)[c:12]3[cH:13][c:14]([OH:18])[cH:15][cH:16][c:17]23)[cH:30][cH:31][c:32]1[F:33]Participants
4
Sources & evidence
- ORD record
- ord-c518a081fb0841678e85b3ac1d581ccb
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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