Methanol → Tert-butyl 4-amino-5-[3-[[1-[3,4-bis[[tert-butyl(dimethyl)silyl]oxy]-5-[3-[(4-methoxyphenyl)methyl]-2,4-dioxopyrimidin-1-yl]oxolan-2-yl]-1-hydroxy-3-[(2-methylpropan-2-yl)oxy]-3-oxopropan-2-yl]amino]propylamino]-5-oxopentanoate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH:8]([CH:37]([CH:38]([NH:39][CH2:40][CH2:41][CH2:42][NH:43][C:44]([CH:45]([NH:46][C:47](=[O:48])[O:49][CH2:50][c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[CH2:57][CH2:58][C:59](=[O:60])[O:61][C:62]([CH3:63])([CH3:64])[CH3:65])=[O:66])[C:67](=[O:68])[O:69][C:70]([CH3:71])([CH3:72])[CH3:73])[OH:74])[O:9][CH:10]([n:20]2[c:21](=[O:36])[n:22]([CH2:27][c:28]3[cH:29][cH:30][c:31]([O:34][CH3:35])[cH:32][cH:33]3)[c:23](=[O:26])[cH:24][cH:25]2)[CH:11]1[O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:75])[CH3:76].[CH3:77][OH:78]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH:8]([CH:37]([CH:38]([NH:39][CH2:40][CH2:41][CH2:42][NH:43][C:44]([CH:45]([NH2:46])[CH2:57][CH2:58][C:59](=[O:60])[O:61][C:62]([CH3:63])([CH3:64])[CH3:65])=[O:66])[C:67](=[O:68])[O:69][C:70]([CH3:71])([CH3:72])[CH3:73])[OH:74])[O:9][CH:10]([n:20]2[c:21](=[O:36])[n:22]([CH2:27][c:28]3[cH:29][cH:30][c:31]([O:34][CH3:35])[cH:32][cH:33]3)[c:23](=[O:26])[cH:24][cH:25]2)[CH:11]1[O:12][Si:13]([CH3:14])([CH3:15])[C:16]([CH3:17])([CH3:18])[CH3:19])([CH3:75])[CH3:76]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-13e50d519b5a4dff8a217c8ec4f62c36
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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