Ethyl (+/-)-10,11-dihydro-10-hydroxy-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate → Ethyl (+/-)-10,11-dihydro-7-fluoro-3-methoxy-5H-dibenzo[a,d]cycloheptene-10-acetate
Reaction equation
[F:1][c:2]1[cH:3][c:4]2[c:5]([cH:24][cH:25]1)[C:6]([CH2:17][C:18](=[O:19])[O:20][CH2:21][CH3:22])([OH:23])[CH2:7][c:8]1[c:9]([cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]1)[CH2:10]2.[OH:26][C:27]1([CH2:28][C:29]([O:30][CH2:31][CH3:32])=[O:33])[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2[CH2:40][c:41]2[cH:42][c:43]([O:44][CH3:45])[cH:46][cH:47][c:48]2[CH2:49]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([cH:24][cH:25]1)[CH:6]([CH2:17][C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:7][c:8]1[c:9]([cH:11][c:12]([O:15][CH3:16])[cH:13][cH:14]1)[CH2:10]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8a896406eead4f278e40dbfcf8c3f205
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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